ChemInform Abstract: Phosphorylated and Thiophosphorylated Heterocyclic Hydrazines.

Abstract

Die (Thio)Phosphorsäurehydrazide (Ia)‐(Ic) reagieren mit "Lactimethern (II) zu den phosphorylierten Hydrazinen (III)‐(V).

2,3,4,5-Tetrahydropyridine (Δ1-piperideine) and its derivatives. Synthesis and chemical properties

“…135 The reactions of the imidate 6a with O-alkyl phosphorothioic acid hydrazides 163 occur as substitution of the methoxy group by the hydrazide residue and give N,N H -disubstituted hydrazine derivatives 164. 136 The reaction of the imidate 6a with cis-2-aminocyclohexanecarboxylic acid in boiling ethanol affords the product of substitution of the methoxy group 165 in 84% yield. 137 Compounds 166 and 167, patented as animal growth stimulators, have been prepared by the reaction of the imidate 6a with primary or secondary amines.…”

Five-, Six-, and Seven-membered Lactim Ethers. Methods of Synthesis and Chemical Properties. (Review)

“…Thus, the lactim ether 86 reacts readily with the aryl(hetaryl)hydrazines 87, forming the condensation products 88 [125]. The products 93 [127] and 94 [126] were obtained from lactim ethers and the salts 91 and 92 respectively. It should be noted in conclusion that many of the compounds synthesized by the reactions of lactim ethers with amines exhibit a wide range of biological activity: They are inhibitors of the coagulation of blood [102,[104][105][106][109][110][111][112], exhibit hypoglycemic activity [91, 93-95, 104, 108, 109], antiviral activity [92,93,103], anti-inflammatory activity [104], antitumor activity [119], and antidiabetic activity [92], and have also been recommended as fungicides [87,125,128] or additives that increase the productivity of animals [100].…”