ChemInform Abstract: Products from Heterodiene Synthesis and 1,3‐Cycloaddition in the Reaction of N,N‐Disubstituted 2‐Aminooxazoles with Maleimide.

Abstract

Products from Heterodiene Synthesis and 1,3-Cycloaddition in the Reaction of N,N-Disubstituted 2-Aminooxazoles with Maleimide. -N,N-Disubstituted 2-aminooxazoles (I) react with maleimides (II) in two directions: heterodiene synthesis with the formation of imides of 2aminopyridine-3,4-carboxylic acids and/or 1,3-cycloaddition forming imides of 2-amino-5-acyl-pyrrolidinedicarboxylic acids. The main direction of the reaction depends on the substitution pattern of initial compound (I) and on the reaction conditions (solvent, temperature). -(KONDRAT'EVA, G. YA.; AITZHANOVA, M. A.; BOGDANOV, V. S.; STASHINA, G. A.; SEDISHEV, I. P.; Chem. Heterocycl.