ChemInform Abstract: REACTION OF NINHYDRIN WITH UREA AND N‐SUBSTITUTED UREAS

Abstract

Ninhydrin (I) reagiert mit Harnstoff (IIa) bzw. den Derivaten (IIb) und (IIc) in siedendem Benzol zu den Imidazolderivaten (IIIa)‐(IIIc).

Quantitative Reaction Cascades of Ninhydrin in the Solid State

“…Quantitative 2-cascades with ureas: Ureas (11) and more easily thioureas (11) are well suited for substitution and addition to 1 (Scheme 5). The interesting heterocyclic bisAbstract in German: Kristallines Ninhydrin (1) geht mit Dimedon, l-Prolin, drei o-Phenylendiaminen, o-Mercaptoanilin, zwei Harnstoffen, drei Thioharnstoffen und 3-Aminocrotons‰uremethylester abfallfreie Kaskadenreaktionen im festen Zustand ein.…”

“…bm, 45 min, RT 100 91 [9] c mortar, 3 d 100 92 [10,11] The packing under the (100) double layers is shown in Figure 2. The molecules 7 a have to penetrate through the double layers from the top, react and spread along the cleavage plane where the functional groups are shielded.…”