ChemInform Abstract: Rearrangement of 2‐Bromo‐1‐(bromomethyl)ethyl Esters under Basic Conditions: Scope and Mechanism.

Abstract

Rearrangement of 2-Bromo-1-(bromomethyl)ethyl Esters under Basic Conditions: Scope and Mechanism. -The title reaction proceeds through formation of a transient dioxolane intermediate followed by hydrolysis with aqueous acid, which triggers ring opening and rearrangement into the final products. -(ALLIOT, J.; GRAVEL, E.; DORIS*, E.; Synthesis 45 (2013) 20, 2861-2866, http://dx.doi.org/10.1055/s-0033-1339649 ; Serv. Chim. Bioorg. Marquage, CEA/Saclay, iBiTecS, F-91191 Gif-sur-Yvette, Fr.; Eng.) -Mais 09-033