ChemInform Abstract: Regioselective Acylations at the 2 and 6 Position of N‐Acetylindole.

Abstract

Regioselective Acylations at the 2 and 6 Position of N-Acetylindole.-Preformation of an AlCl 3 -complex of 1-acetylindole (I) allows a selective acylation in the 6-position. On the other hand, addition of (I) to a mixture of bis acid chlorides (V) and AlCl 3 leads to 2-acylated products selectively. -(CRUZ, ROSIMEIRE P. A.; OTTONI, OLIVIA; ABELLA, CARLOS A. M.; AQUINO, LIGIA B..; Tetrahedron Lett. 42 (2001) 8,