ChemInform Abstract: Regioselective Reaction of 5,6‐Dialkyl‐2‐halopyridine‐3,4‐dicarbonitriles with Ammonia.

Abstract

Regioselective Reaction of 5,6-Dialkyl-2-halopyridine-3,4-dicarbonitriles with Ammonia. -Reaction of the title compounds (I) with alcoholic ammonia provides selective access to pyrrolopyridine derivatives (II) or nucleophilic substitution products (III), depending on the conditions. -(MAKSIMOVA*, V. N.; ERSHOV, O. V.; LIPIN, K. V.; EREMKIN, A. V.; NASAKIN, O. E.; Russ. J. Org. Chem. 48 (2012) 3, 426-429, http://dx.doi.org/10.1134/s1070428012030153 ; Chuvash Ul'yanov State Univ., Cheboksary 428015, Russia; Eng.) -C. Cyrus