ChemInform Abstract: Ring‐Closing Metathesis of Vinyl Fluorides Towards α‐Fluorinated α,β‐Unsaturated Lactams and Lactones.

Abstract

Ring-Closing Metathesis of Vinyl Fluorides Towards -Fluorinated ,-Unsaturated Lactams and Lactones. -It is demonstrated, that ring-closing metathesis of azadienes having a fluorine substituent is successfully applied to the synthesis of a variety of mono-and bicyclic N-heterocycles. The method is extended to the synthesis of 6-and 7-membered O-heterocycles as well. -(MARHOLD, M.; STILLIG, C.; FROEHLICH, R.; HAUFE*, G.; Eur. J. Org. Chem. 2014, 26, 5777-5785, http://dx.doi.org/10.1002/ejoc.201402535 ; Org.-Chem. Inst., Westfael. Wilhelms Univ., D-48149 Muenster, Germany; Eng.) -Mais 10-055