ChemInform Abstract: Ruthenium‐Catalyzed Reconstitutive Condensation. Application to Functionalized Steroid Side Chains.

Trost, Barry M.; Kulawiec, Robert J.; Hammes, Alf

doi:10.1002/chin.199324272

Cited by 1 publication

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…First B. M. Trost showed that using the CpRu(PPh 3 ) 2 Cl/NH 4 PF 6 catalytic system, the addition of allylic alcohols to terminal alkynes was possible and took place affording b,c-unsaturated ketones, via addition of allyl alcohol to the vinylidene intermediate and C-O bond cleavage and allyl migration (Eq. 14) [74][75][76][77].…”

Section: ð12þmentioning

confidence: 99%

Early Steps of Homogeneous Catalysis in Rennes: Carbon Dioxide Incorporation, Alkyne Activation and Ruthenium Catalysis

Dixneuf

2014

Catal Lett

View full text Add to dashboard Cite

This review reports the first discoveries in homogeneous catalysis in Rennes. Ruthenium(II) catalysts are shown to promote the activation of terminal alkynes and the synthesis of vinylcarbamates on addition of CO 2 and amines. The ruthenium-vinylidene are the key catalytic species. Applications to the addition of carboxylic acids to alkynes have opened the access to various enolesters and dienylesters via controlled catalyzed Markovnikov or anti-Markonikov additions. The catalytic synthesis of a-methylene cyclic carbonates and oxazolidinones from propargylic alcohols and CO 2 is presented and shown to lead to allene derivatives via palladium catalysis. Cp*RuX(COD) catalyst promote the head to tail oxidative couplings of alkene with alkyne, and the synthesis of functional dienes via 1,4 addition of H-nucleophiles to the biscarbene-ruthenium intermediate arising from head to head couplings of alkynes, whereas Cp*RuL 2 ? catalysts favour activation of alkynes via vinylidene intermediate.

show abstract

Section: ð12þmentioning

confidence: 99%

Early Steps of Homogeneous Catalysis in Rennes: Carbon Dioxide Incorporation, Alkyne Activation and Ruthenium Catalysis

Dixneuf

2014

Catal Lett

View full text Add to dashboard Cite

show abstract

ChemInform Abstract: Ruthenium‐Catalyzed Reconstitutive Condensation. Application to Functionalized Steroid Side Chains.

Cited by 1 publication

References 1 publication

Early Steps of Homogeneous Catalysis in Rennes: Carbon Dioxide Incorporation, Alkyne Activation and Ruthenium Catalysis

Early Steps of Homogeneous Catalysis in Rennes: Carbon Dioxide Incorporation, Alkyne Activation and Ruthenium Catalysis

Contact Info

Product

Resources

About