ChemInform Abstract: Selective Electrosynthesis of (Trimethylsilyldifluoro)methylbenzene, a PhCF₂‐Precursor; Conditions for a Molar Scale Preparation without HMPA.

Abstract

Selective Electrosynthesis of (Trimethylsilyldifluoro)methylbenzene, a PhCF 2 -Precursor; Conditions for a Molar Scale Preparation without HMPA.-Electrolytic reduction of trifluoromethylbenzene (I) and trimethylsilyl chloride (II) by the sacrificial anode technique provides an efficient synthesis of (trimethylsilyldifluoro)methylbenzene (III). Prolonged electrolysis allows, according to the charge passed, the preparation of the corresponding bisand tris-silyl derivatives (IV) and (V). -(CLAVEL, P.; LEGER-LAMBERT, M.-P.; BIRAN, C.; SEREIN-SPIRAU, F.; BORDEAU, M.; ROQUES, N.; MARZOUK, H.; Synthesis (1999) 5, 829-834; Lab. Chim. Org. Organomet., CNRS, Univ. Bordeaux, F-33405 Talence, Fr.; EN)