ChemInform Abstract: Sequential Multicomponent reactions and a Cu‐Mediated Rearrangement: Diastereoselective synthesis of Tricyclic Ketones.

Abstract

Sequential Multicomponent reactions and a Cu-Mediated Rearrangement: Diastereoselective synthesis of Tricyclic Ketones. -The first diastereoselective Cu-mediated rearrangement of bisamides containing a thiazolidiene substructure is reported which provides complex heterotricyclic annulated and bridged systems consisting of an imidazolidin-4-one and a thiomorpholine cycle. -(KROEGER, D.; FRANZ, M.; SCHMIDTMANN, M.; MARTENS*, J.; Org. Lett. 17 (2015) 23, 5866-5869, http://dx.