ChemInform Abstract: Stereoselective Bromocyclization of Allylated Aldoxime Ethers

Abstract

Stereoselective Bromocyclization of Allylated Aldoxime Ethers -Bromination of O-allylated aldoxime ethers having a trans substituted allyl group with Br(collidine) 2PF6 induces an efficient diastereoselective cyclization to give 5-bromooxazine derivatives. The cis-substituted allyl substrate (VII) produces a mixture from which the isoxazoline (VIII) can be isolated. -(EGART, B.; CZEKELIUS*, C.; Chem. -Asian J. 9 (2014) 8, Special Issue, 2088-2091, http://dx.