ChemInform Abstract: Studies on Synthetic Ionophores. Part 6. Synthesis of Polyether Carboxylic Acids and Their Use as Carriers for Alkali Metal Ion Transport Through Liquid Membrane.

Abstract

Polyethers such as (I)‐(III) are prepared by conventional procedures mainly based on the Williamson ether synthesis.

Potassium Salt of a Synthetic Carboxylic Ionophore

“…To understand the complexation properties of ion carders and how these acyclic compounds utilize conformation for optimum complexation with a guest cation, the crystal structures of various complexes have been determined using X-rays (Duesler & Paul, 1983, and references therein). We have synthesized a series of w-hydroxycarboxylic acids as model compounds for the natural ionophores to investigate the relationship between the primary molecular structures and transport properties (Kuboniwa et al, 1985;Kuboniwa, Yamaguchi, Nakahama, Hirao & Yamazaki, 1982;Yamaguchi et al, 1988Yamaguchi et al, , 1989Yamazaki, Hirao & Nakahama, 1979;Yamazaki, Nakahama, Hirao & Negi, 1978). Among the compounds, (1) and (2), which have eight and five ethereal O atoms, respectively, show relatively high K+-ion selectivity.…”