Chemischer Informationsdienst. Organische Chemie
 1970
DOI: 10.1002/chin.197049343
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ChemInform Abstract: SYNTH. MIT 2‐METHYLCHINOLIN‐4‐CARBONSAEURE

A. E. Lipkin1,
Z. P. Bespalova2

Abstract: Die aus Isatin und Aceton gut zugängliche 2‐Methylchinolin‐4‐carbonsäure (I) reagiert mit äquimolaren Mengen aromatischer Aldehyde (II) in Gegenwart von Essigsäureanhydrid zu den 2‐Viny1chinolin‐4‐carbonsäuren (III) (60 ‐ 70% Ausbeute), von denen nur das Styryl‐Derivat antimikrobielle Wirkung besitzt.

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