ChemInform Abstract: SYNTHESIS AND ANTIFUNGAL ACTIVITY OF OXAZOLONES

Manrao, M. R.; Sharma, Renu; Dhir, B. S.; Kalsi, P. S.

doi:10.1002/chin.198305206

Cited by 2 publications

(3 citation statements)

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“…The reaction of benzalaniline and substituted benzalanilines with sulphene gives addition product 1,4-BT.1,4-Benzothiazine 5 , the heterocyclic compounds containing nitrogen and Sulphur in the six membered ring system. It has been reported to possess antifungal activity [6][7][8] . The Introduction of certain groups/atoms like -OH, -CH 3 , -OC 2 H 5 , -Cl etc.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Study of Anti Fungal Activity of 1,4-benzothiazines Derivatives

Jain

2023

Preprint

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Imines forms an important class of heterocyclic compounds such as1,4-Benzothiazine and its derivatives which shows wide range of biological activities such as antimicrobial, antifungal etc. Therefore, some new benzothiazine derivatives were synthesized by using benzanilide and substituted benzanilides with sulphene, generated in situ from methane sulphonyl chloride and triethylaminehydroxylchloride, as a starting material. The synthesized 1,4-benzothiazines (Ia -Va) were tested in vitro for their antifungal activity against Alternaria alternate, Curvularia lunata, Fusarium oxysporum and Myrothecium roridum by employing the standard technique of spore germination inhibition at various concertation’s. Some of the compounds have shown promising antifungal activity against test fungi.

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Section: Introductionmentioning

confidence: 99%

Synthesis and Study of Anti Fungal Activity of 1,4-benzothiazines Derivatives

Jain

2023

Preprint

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“…The presence of electron releasing groups such as methoxy 4 , ethoxy 5 , hydoxy 6 etc. in the phenyl ring increases the activity of parent compound like Schiff bases and thiazolidinones.…”

Section: Introductionmentioning

confidence: 99%

“…in the phenyl ring increases the activity of parent compound like Schiff bases and thiazolidinones. The present investigation was carried out to study the effect of hydroxyl group in the ortho position of C-phenyl ring on the fungitoxicity of 1,2,4-oxadiazolines because it has been reported that the presence of OH group in ortho position of N-phenyl ring increases the activity of 1,2,4-oxadiazoline 7 manifold. The results of this study are being communicated in this paper.…”

Section: Introductionmentioning

confidence: 99%