ChemInform Abstract: Synthesis of 1,2‐Diamines, 2‐Imidazolidinones, and 2‐ Imidazolidinethiones from α‐Halo Imines.

Abstract

Synthesis of 1,2-Diamines, 2-Imidazolidinones, and 2-Imidazolidinethiones from α-Halo Imines.-Vicinal diamino compounds such as (III) are prepared from the α-chloro imines (I) by azidation and subsequent reduction. They are cyclized with urea (IV) and carbon disulfide, yielding the title compounds (V) and (VII) respectively. - (DE KIMPE, N.; D'HONDT, L.; Synthesis (1993) 10, 1013-1017; Dep. Org. Chem., Fac. Agric. Appl. Biol. Sci., Univ., 9000 Gent, Belg.; EN)