ChemInform Abstract: Synthesis of 1,3‐Disubstituted Imidazo[1,5‐a]pyridines from Amino Acids via Catalytic Decarboxylative Intramolecular Cyclization.

Abstract

2‐Aryloylpyridines or quinolines efficiently react with aryl or alkyl substituted α‐amino acids, thus offering not only a novel approach to 1,3‐diaryl substituted imidazo[1,5‐a]pyridines, but also to 3‐alkyl‐1‐aryl substituted derivatives which are difficult to access by previously developed methods.