ChemInform Abstract: Synthesis of 3,5‐Lutidine by Catalytic Transfer Hydrogenation via 1,2, 5,6‐Tetrahydropyridine.

Abstract

Synthesis of 3,5-Lutidine by Catalytic Transfer Hydrogenation via 1,2, 5,6-Tetrahydropyridine.-Substituted pyridines, e.g. 3,5-lutidine (II), which can be used as starting material for the synthesis of anti-ulcer drug omeprazole, are prepared from the corresponding tetrahydropyridines (I) by a novel catalytic transfer-hydrogenation procedure. -(SATHE, D. G.; KULKARNI, V. M.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 33 (1994) 10, 986-987; Dep. Chem. Technol., Univ. Bombay, Bombay 400 019, India; EN)