ChemInform Abstract: Synthesis of 6‐Bromo‐2‐arylindoles Using 2‐Iodobenzoic Acid as Precursor.

Abstract

Synthesis of 6-Bromo-2-arylindoles Using 2-Iodobenzoic Acid as Precursor. -Sonogashira coupling of the carbamate (II) followed by Bu4NF-promoted cyclization allows the preparation of pharmacologically interesting 2-arylindoles bearing a bromine at C-6 position. -(VALOIS-ESCAMILLA, I.; ALVAREZ-HERNANDEZ*, A.; RANGEL-RAMOS, L. F.; SUAREZ-CASTILLO, O. R.; AYALA-MATA, F.; ZEPEDA-VALLEJO, G.; Tetrahedron Lett. 52 (2011) 29, 3726-3728, http://dx.doi.org/10.1016/j.tetlet.2011.05.040 ; Cent. Invest. Quim., Univ. Auton. Estado Hidalgo, 42184 Hidalgo, Mex.; Eng.) -Mais 44-105