ChemInform Abstract: Synthesis of 6‐Hydroxymethylpterin α‐ and β‐D‐Glucosides.

Abstract

Synthesis of 6-Hydroxymethylpterin αand β-D-Glucosides. -The selective αand β-glycosylation of a pterin derivative is achieved by treatment of key precursor (I) with α-D-glycosyl donors (II) and (V). Removal of the protecting groups of β-D-glucoside (III) is performed by successive cleaving of the benzoyl groups, the dimethylaminomethylene group, and the Npe group. A four-step procedure is employed to remove the protecting groups of α-D-glucoside (VI). -(HANAYA*, T.; BABA, H.; EJIRI, K.; YAMAMOTO, H.; Heterocycles 80 (2010) 2, 1013-1025,