The antioxidation, anticorrosion, protecting, and antimicrobial properties of previously synthesized nitrogen-, sulfur-, and phosphorus-substituted derivatives of 2-hydroxy-5-tert-alkyl thiophenols containing several functional groups and heteroatoms have been studied. It is shown that these compounds can be recommended as multifunctional oil additives. Improvement in performance characteristics of lubricating oils, in addition to refinement of base oil production technology, can be achieved by introducing additives into them. A huge number of organic compounds containing various functional groups in the molecule, which are usable as additives, have been synthesized and studied comprehensively. It was found that some nitrogen-, sulfur-, and phosphorous-containing organic compounds having a specific structure improve the performance properties of oils, thanks to which they are usable as oil additives [1].Additives recommended for improving some properties of oils often produce adverse effect on other properties. Because of this, it is essential to select effective additives that improve the whole range of performance properties. Such additives may be compounds that contain in a single molecule several functional groups of different kinds simultaneously.The purpose of this work was to study derivatives of 2-hydroxy-5-tert-alkyl thiophenol [2-4] and 2-hydroxy-5-methoxythiophenols [5] synthesized by us earlier for use as antioxidation, anticorrosion, antirusting, and antimicrobial additives in the mineral oil M-11.The antioxidative properties of additives as a component of vaseline oil (petroleum jelly) were studied using chemiluminescence method at 200°C in an apparatus built at the Institute of Additives Chemistry, Azerbaijan National Academy of Sciences, on the principle of action of the chemiluminescence unit SNK-7 developed at the Institute of Chemical Physics, Academy of Sciences of the USSR [6]. This method is based on weakening by an antioxidant of luminescence of the oil caused by the action of peroxide radicals.