ChemInform Abstract: SYNTHESIS OF BIOLOGICALLY ACTIVE CYCLOPENTENO(D)SELENAZOLE DERIVATIVES AND THEIR THIO ANALOGS

Abstract

Thio‐semicarbazone bzw. Seleno‐semicarbazone (I) reagieren mit α‐Brom‐cyclopentanon (II) zu den Cyclopenteno‐thiazolen bzw. den Cyclopentenoselenazolen (III).

Microwave-assisted synthesis and antitumor evaluation of a new series of thiazolylcoumarin derivatives

“…2-(3-Bromo-4-hydroxybenzylidene)hydrazinocarbothioamide (4i): Yield 67%, m.p. 169-172 °C (Tsurkan et al, 1982[ 72 ]), (methanol), C 8 H 8 BrN 3 OS. 1 H NMR (DMSO- d 6 ) δ 6.95-8.20 (m, 6H, Ar-H, NH 2 , CH=N), 10.75 (s, 1H, OH), 11.30 (s, 1H, NH).…”