Keywords: Alkynes / Copper / Click chemistry / Multicomponent reactions / Regioselectivity / Zeolites Copper(I)-modified zeolites, especially Cu I -USY, proved to be very efficient catalysts in multi-component reactions of epoxides with sodium azide and terminal alkynes. Such catalysts allow highly regio-and stereoselective syntheses of hydroxymethylated triazoles. These heterogeneous, modified zeolites can easily be recovered and reused. Moreover, the