ChemInform Abstract: Synthesis of Chiral 3‐Acyl‐4‐alkylthiazolidine‐2‐thiones as Enantioselective Acylating Agents.

Abstract

Synthesis of Chiral 3-Acyl-4-alkylthiazolidine-2-thiones as Enantioselective Acylating Agents.-Title compounds, e.g. (V) are used for the enantioselective benzoylation of racemic amines and amino acids, such as (VI). Yields are high (78-94%) and enantioselectivities are moderate to good (48-68% e.e.). -(YADAV, L. D. S.; DUBEY, SUMAN; Indian J. Chem., Sect. B: Org.