ChemInform Abstract: Synthesis of Heteroarylogous 1H‐Indole‐3‐carboxamidines via a Three‐Component Interrupted Ugi Reaction.

Abstract

Synthesis of Heteroarylogous 1H-Indole-3-carboxamidines via a Three-Component Interrupted Ugi Reaction. -The novel one-pot multicomponent reaction is based on the reaction of N-alkyl-N-(1H-indol-2-ylmethyl)amines, with various carbonyl compounds, such as aldehydes including formaldehyde or cyclohexenone, and variously functionalized isocyanides. -(LA SPISA, F.; MENEGHETTI, F.; POZZI, B.; TRON*, G. C.; Synthesis 47 (2015) 4, 489-496, http://dx.doi.org/10.1055/s-0034-1378921 ; Dip. Sci. Farm., Univ. Studi Piemonte