ChemInform Abstract: Synthesis of Imidazo[4,5‐d]oxazolo[3,4‐a]pyridines. New Heterocyclic Analogues of Lignans.

Abstract

Synthesis of Imidazo [4,5-d]oxazolo [3,4-a]pyridines. New Heterocyclic Analogues of Lignans.-The preparation of new analogues of lignans (VI) and (VII) carrying an imidazole ring is achieved starting from L-histidinol (I). The products lack the cytotoxicity displayed by related podophyllotoxines and azatoxin.