ChemInform Abstract: Synthesis of Optically Active Partly gem‐Difluorinated Allylic Alcohols via [2,3]‐Wittig Rearrangements and Lipase‐Catalyzed Reaction.

Abstract

2000 halogen compounds halogen compounds (acyclic compounds) P 0030 36 -064 Synthesis of Optically Active Partly gem-Difluorinated Allylic Alcohols via [2,3]-Wittig Rearrangements and Lipase-Catalyzed Reaction. -[2,3]-Wittig rearrangement of 1,1,2-trifluoroallylic ethers (I) gives novel dienols. Lipase-catalyzed resolution of their acetates (V) and (VI) is successful in the case of the latter substrate. -(ITOH, TOSHIYUKI; KUDO,