ChemInform Abstract: Synthesis, Stereochemistry, and Pharmacological Activity of 1‐(2‐(3,4‐Dimethoxyphenyl)ethyl)‐2‐methyl‐4‐ketodecahydroquinoline and Corresponding Acetylenic Alcohols.

Abstract

Reaction of the propenyl cyclohexenyl ketone (I) with the dimethoxyphenethylamine (II) gives the perhydroquinolone (III) which is coupled with the acetylene (IV), producing the ethynyl carbinols (V) and (VI).