ChemInform Abstract: The Role of a Lewis Acid in the Nenitzescu Indole Synthesis.

Abstract

Indole derivatives R 0140The Role of a Lewis Acid in the Nenitzescu Indole Synthesis. -The new method for the preparation of 5-hydroxyindoles is based on enamine component activation via its ZnCl2-complex followed by deprotection. The amount of ZnCl2 depends on the nature of the enamine. -(VELEZHEVA*, V. S.; SOKOLOV, A. I.; KORNIENKO, A. G.; LYSSENKO, K. A.; NELYUBINA, Y. V.; GODOVIKOV, I. A.; PEREGUDOV, A. S.; MIRONOV, A. F.; Tetrahedron Lett. 49 (2008) 50, 7106-7109; Nesmeyanov Inst. Organoelem. Compd., Russ. Acad. Sci., Moscow 119991, Russia; Eng.) -Mais 13-107