ChemInform Abstract: Total Synthesis of (+)‐Desoxoprosopinine via the Intramolecular Reaction of γ‐Aminoallylstannane.

Abstract

Total Synthesis of (+)-Desoxoprosopinine via the Intramolecular Reaction of γ-Aminoallylstannane. -A synthesis of (+)-desoxoprosopinine (V) using the L-glutamic acid derived allylic amine (I) as chiral source is reported. Key step is a moderately diastereoselective intramolecular reaction of the γ-aminoallylstannane (II). -(KADOTA, I.; KAWADA, M.; MURA-MATSU, Y.; YAMAMOTO, Y.; Tetrahedron Lett. 38 (1997) 42, 7469-7470; Dep. Chem., Fac. Sci., Tohoku Univ., Aoba, Sendai 980, Japan; EN)