Chemisorption of Glycidyl Spacer on Magnetic Nanoparticles and Immobilization of Albumin and Quinacrine

Королев, Д. В.; Postnov, V. N.; Romanova, T. N.; Zorin, V N; Shulmeyster, Galina; Naumysheva, E. B.; Evreinova, N. V.; Murin, I. V.

doi:10.1134/s1070363220030111

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Approaches To Theranostics Current Trends and Tools1

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“…The immobilization of active substances and contrasts on the surface of nanocarriers can be achieved by using the functional group or by other methods. The most frequently used functional groups are amino, carboxyl, and (less commonly) glycidine groups [6,7]. Albumin is sometimes used as a spacer, acting as a transport protein with many functional groups [8].…”

Section: Approaches To Theranostics Current Trends and Toolsmentioning

confidence: 99%

The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms

et al. 2021

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This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of nanoparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.

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Section: Approaches To Theranostics Current Trends and Toolsmentioning

confidence: 99%