Chemistry and engineering of brush type polymers: Perspective towards tissue engineering

Açarı, İdil Karaca; Sel, Evren; Özcan, İmren; Ateş, Burhan; Köytepe, Süleyman; Thakur, Vijay Kumar

doi:10.1016/j.cis.2022.102694

Cited by 24 publications

(10 citation statements)

References 132 publications

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“…Brush polymers are widely used in tissue repair and have a great influence on cell culture or the production of cell layers, preventing cell or microbe adhesion (anti-fouling effect). 182…”

Section: Application Of Different Adhesive Materials In the Biomedica...mentioning

confidence: 99%

“…Brush polymers are widely used in tissue repair and have a great influence on cell culture or the production of cell layers, preventing cell or microbe adhesion (antifouling effect). 182 Li et al developed a bioadhesive hydrogel (GMO) used for conjunctival transplantation based on a semi-interpenetrating polymer network (SIPN) comprised of methacrylate gelatin (Gelma) and oxidized hyaluronic acid (OHA). 183 Gelma was used as a rigid support and OHA was used as the interface initiator.…”

Section: Tissue Repairmentioning

confidence: 99%

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Recent advances in adhesive materials used in the biomedical field: adhesive properties, mechanism, and applications

Liu

2023

J. Mater. Chem. B

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“…Brush polymers are widely used in tissue repair and have a great influence on cell culture or the production of cell layers, preventing cell or microbe adhesion (anti-fouling effect). 182…”

Section: Application Of Different Adhesive Materials In the Biomedica...mentioning

confidence: 99%

Section: Tissue Repairmentioning

confidence: 99%

Recent advances in adhesive materials used in the biomedical field: adhesive properties, mechanism, and applications

Liu

2023

J. Mater. Chem. B

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“… Applications of brush-type polymer coatings (a; drug delivery systems, b; membrane applications, c; smart membrane and surface applications, d; biosorption, e; antibacterial surfaces, f; biosensor applications, g; cell adhesive surfaces, h; biocompatible coatings, i; tissue engineering applications, and j; antifouling surfaces) ( Left ). Brush-type polymer structures are commonly used to prevent microbes from adhering to surfaces ( Right ) (reprinted with permission from Açarı et al, 2022 [ 146 ]). …”

Section: Figurementioning

confidence: 99%

Antiviral Peptides in Antimicrobial Surface Coatings—From Current Techniques to Potential Applications

Jabeen

Biswas

Islam

et al. 2023

Viruses

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The transmission of pathogens through contact with contaminated surfaces is an important route for the spread of infections. The recent outbreak of COVID-19 highlights the necessity to attenuate surface-mediated transmission. Currently, the disinfection and sanitization of surfaces are commonly performed in this regard. However, there are some disadvantages associated with these practices, including the development of antibiotic resistance, viral mutation, etc.; hence, a better strategy is necessary. In recent years, peptides have been studied to be utilized as a potential alternative. They are part of the host immune defense and have many potential in vivo applications in drug delivery, diagnostics, immunomodulation, etc. Additionally, the ability of peptides to interact with different molecules and membrane surfaces of microorganisms has made it possible to exploit them in ex vivo applications such as antimicrobial (antibacterial and antiviral) coatings. Although antibacterial peptide coatings have been studied extensively and proven to be effective, antiviral coatings are a more recent development. Therefore, this study aims to highlight antiviral coating strategies and the current practices and application of antiviral coating materials in personal protective equipment, healthcare devices, and textiles and surfaces in public settings. Here, we have presented a review on potential techniques to incorporate peptides in current surface coating strategies that will serve as a guide for developing cost-effective, sustainable and coherent antiviral surface coatings. We further our discussion to highlight some challenges of using peptides as a surface coating material and to examine future perspectives.

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“…Due to their unique properties, they have been widely employed in various applications, such as organic electronic devices 1 where conjugated polymers are used as grafts, and surface engineering, for example, lubricants, 2,3 adhesives, 4 and high‐performance polymer composites 5 . Remarkably, a broad range of smart materials has been designed based on responsive polymer brushes, 6 which has led to the innovation of novel sensors, 7 separation membranes, 8 and biomedical devices, 9 for example, used in drug delivery, 10,11 and tissue engineering 12,13 and so forth.…”

Section: Introductionmentioning

confidence: 99%

polyGraft 1.0: A program for molecular structure and topology generation of polymer‐grafted hybrid nanostructures

Chen

2023

J Comput Chem

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Polymer‐grafted hybrid materials have been ubiquitously employed in various engineering applications. The design of these hybrid materials with superior performances requires a molecularly detailed understanding of the structure and dynamics of the polymer brushes and their interactions with the grafting substrate. Molecular dynamics (MD) simulations are very well suited for the study of these materials which can provide molecular insights into the effects of polymer composition and length, grafting density, substrate composition and curvatures, and nanoconfinement. However, few existing tools are available to generate such systems, which would otherwise reduce the barrier of preparation for such systems to enable high throughput simulations. Here polyGraft, a general, flexible, and easy to use Python program, is introduced for automated generation of molecular structure and topology of polymer grafted hybrid materials for MD simulations purposes, ranging from polymer brushes grafted to hard substrates, to densely grafted bottlebrush polymers. polyGraft is openly accessible on GitHub (https://github.com/nanogchen/polyGraft).

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Chemistry and engineering of brush type polymers: Perspective towards tissue engineering

Cited by 24 publications

References 132 publications

Recent advances in adhesive materials used in the biomedical field: adhesive properties, mechanism, and applications

Recent advances in adhesive materials used in the biomedical field: adhesive properties, mechanism, and applications

Antiviral Peptides in Antimicrobial Surface Coatings—From Current Techniques to Potential Applications

polyGraft 1.0: A program for molecular structure and topology generation of polymer‐grafted hybrid nanostructures

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