Chemistry and Enzymology of Nucleic Acids

The biosynthesis of pyrimidines by mutants of Aerobacter aerogenes

“…Uracil was accumulated, while the carbohydrate component disintegrated rapidly after the splitting off of the pyrimidine base. These observations were similar to those described earlier for purine ribosides (Schlenk, 1949). No indication was found that the action of bacterial pyrimidine nucleoside phosphorylase was preceded by opening of the pyrimidine ring as suggested by Mitchell and…”

“…Michelson, _et (1951) (Loring and Pierce, 1944;Arvidson, » 1949;Schlenk, 1949;Paege and Schlenk, 1950b}.…”