Chemistry of dibenzylideneacetone-palladium(0) complexes

Synthesis of Macropolycycles Comprising Diazacrown and Adamantane Moieties via Pd -Catalyzed Amination Reaction

“…3-and 4-bromobenzyl bromide, 1,7-diaza-15-crown-5 and 1,10-diaza-18-crown-6, BINAP and DavePhos ligands, sodium tert-butoxide were purchased from Aldrich and Acros and used without further purification, Pd(dba) 2 was synthesized according to the method described. [33] 1,3-Bis(aminomethyl)-adamantane and 1,3-bis(2-aminoethyl)adamantane were obtained according to a method described earlier. [25] Dioxane was distilled over NaOH followed by the distillation over sodium under argon, acetonitrile, dichloromethane and methanol were used freshly distilled.…”

Macrobicycles based on cyclen and cyclam containing 1,3-disubstituted adamantane moiety

“…26 Pd(dba) 2 was synthesized according to a known method. 32 Commercial 1,4-dioxane was distilled over NaOH and sodium under argon, dichloromethane and methanol were freshly distilled prior to use. Column chromatography was carried out using silica gel (40-60 mkm) purchased from Fluka.…”

Inversion of the Cis Geometry Requirement for Cytotoxicity in Structurally Novel Platinum(II) Complexes Containing the Bidentate N,O-Donor Pyridin-2-yl-acetate.

“…Elemental analyses and IR, NMR, and mass spectra were obtained as described elsewhere. 20 The compounds Pd2(dba)3‚ CHCl3, 29 [Pd (PPh2CHPPh2CHCOMe)2] (1). (a) To a suspension of Pd2dba3‚ CHCl3 (0.085 g, 0.093 mmol) in 20 mL of CH2Cl2 was added the ylide PPh2CH2PPh2CHCOMe (0.328 g, 0.744 mmol), and the mixture was stirred at room temperature for 10 min.…”