Chemistry of Nitric Oxide Relevant to Biology

McCleverty, Jon A.

doi:10.1021/cr020623q

Cited by 456 publications

(378 citation statements)

References 76 publications

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“…[44] Note that the ν NO value for free NO + is 2377 cm -1 , whereas that for NO is 1875 cm -1 . [45] The Ru-NO stretching vibration in 1 is at 587 cm -1 (586 cm -1 in the sodium salt), in agreement with those of a number of other ruthenium-nitrosyl compounds. [77] [46] The diamagnetic behavior of a polycrystalline sample of 1 and Na 2 [RuCl 5 (NO)]·6H 2 O in the temperature range of 2-300 K in a magnetic field of 1 T provides further evidence for the formulation {Ru(NO)} 6 containing Ru II (S = 0) bonded to NO + (S = 0) or NO 0 (S = ½) coupled antiferromagnetically or through a closed-shell interaction to Ru III (S = ½).…”

Section: Resultssupporting

confidence: 75%

On the Electronic Structure ofmer,trans‐[RuCl₃(1H‐indazole)₂(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

et al. 2013

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The study reported herein focused on the electronic structure of the {Ru(NO)} 6 fragment and characterization of the oxidation state of ruthenium in mer,trans- [RuCl 3 (Hind) (3) were experimentally and theoretically investigated as reference compounds. A complete active space SCF calculation was performed to estimate the extent of antiferromagnetic spin-spin coupling in 1. We found that the closed-shell structure {Ru III (NO) 0 } 6 fits better to the physical/ spectroscopic properties of 1, although {Ru II (NO) + } 6 is formally still suitable for describing the oxidation state of Ru in this entity.

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Section: Resultssupporting

confidence: 75%

On the Electronic Structure ofmer,trans‐[RuCl₃(1H‐indazole)₂(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

et al. 2013

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“…Co(CO) 3 (NO) and spectroscopic grade hexane were purchased from Strem Chemicals Inc. and EMD Chemicals Inc., respectively. All samples were used without further purification.…”

Section: A Sample Preparationmentioning

confidence: 99%

“…24 However, the only photochemical reaction observed via IR studies of Co(CO) 3 (NO) in frozen matrices and in the gas phase is the dissociation of a CO or NO ligand. 25,26,29 The goal of this study is to determine whether a bent-NO complex is formed from visible photolysis of Co(CO) 3 (NO), and, if it is formed, to determine the mechanism for its formation.…”

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confidence: 99%

Direct Observation of Photoinduced Bent Nitrosyl Excited-State Complexes

et al. 2008

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“…[1][2][3][4][5][6] Due to this, ruthenium nitrosyl complexes have emerged as an efficient system for the design of NO donors with potential pharmacological applications. [7][8][9][10] The most common synthetic route to prepare ruthenium nitrosyl complexes is based on the conversion of coordinated NO 2 -into NO + .…”

Section: Introductionmentioning

confidence: 99%

“…

3 complex. Chromatographic studies were carried out and showed that immediately after nitrite complex was dissolved only one species was present with retention time(t R ) of 6.81 minutes.

…”

mentioning

confidence: 99%

Chromatographic Investigation of Ruthenium Nitrosyl Complex: No Interconversion and Reactions With Biological Reductants

Silva¹,

Penha²,

Alencar³

et al. 2018

Quim. Nova

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3 complex. Chromatographic studies were carried out and showed that immediately after nitrite complex was dissolved only one species was present with retention time(t R ) of 6.81 minutes. Addition of H 3 O + to nitrite complex led to the formation of one major peak with t R of 3.92 min supporting nitrosyl complex formation. The reaction of nitrosyl complex with cysteine was also monitored by HPLC and it showed clearly the formation and followed decrease of a peak at 3.38 minute with maximum absorption at 380 nm, consistent with an intermediate complex. Later, it was observed the appearance of a peak at 4.15 minute with absorption band at 470 nm. In contrast to the reaction with cysteine, methionine did not show the formation of any intermediate. The use of HPLC was an important tool to support mechanistic assumptions for nitrosyl reactions.

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Chemistry of Nitric Oxide Relevant to Biology

Cited by 456 publications

References 76 publications

On the Electronic Structure ofmer,trans‐[RuCl₃(1H‐indazole)₂(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

On the Electronic Structure ofmer,trans‐[RuCl₃(1H‐indazole)₂(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

Direct Observation of Photoinduced Bent Nitrosyl Excited-State Complexes

Chromatographic Investigation of Ruthenium Nitrosyl Complex: No Interconversion and Reactions With Biological Reductants

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Chemistry of Nitric Oxide Relevant to Biology

Cited by 456 publications

References 76 publications

On the Electronic Structure ofmer,trans‐[RuCl3(1H‐indazole)2(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

On the Electronic Structure ofmer,trans‐[RuCl3(1H‐indazole)2(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

Direct Observation of Photoinduced Bent Nitrosyl Excited-State Complexes

Chromatographic Investigation of Ruthenium Nitrosyl Complex: No Interconversion and Reactions With Biological Reductants

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On the Electronic Structure ofmer,trans‐[RuCl₃(1H‐indazole)₂(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study

On the Electronic Structure ofmer,trans‐[RuCl₃(1H‐indazole)₂(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study