Chemodiversity and Antibacterial Activity of the Essential Oil of Leaves of Croton argyrophyllus

Abstract

The Croton argyrophyllus leaf essential oil has anti-inflammatory, antioxidant, cytotoxic among other activities. However, there are chemical composition variations in the literature. This work reports the first study of the intraspecific chemical variation of C. argyrophyllus population from Pernambuco state, Brazil. The essential oils of nine specimens (OCA1 to OCA9) were analyzed by GC/MS and NIR to identify the chemical compositions and to verify the similarities between the analyzed samples. These analyses resulted in the identification of bicyclogermacrene (mean 38.42 %), (Z)-caryophyllene (mean of 14.06 %), epi-longipinanol (mean of 9.78 %) and germacrene B (mean of 9.1 %) as the major constituents, as well as the same chemical markers for all oil samples. However, these are different to those that were previously registered in the literature for C. argyrophyllus essential oil. The data obtained from the analysis by NIR spectroscopy were treated by PCA and HCA and showed similarities in the chemical samples' profile. By statistical analyses three clusters were obtained: OCA1-6, OCA7-8 and OCA9. All these groups were potentially active against Staphylococcus aureus. However, the OCA7-8 group was the most active.

Chemical Constituents of the Essential Oil from Ecuadorian Endemic Species Croton ferrugineus and Its Antimicrobial, Antioxidant and α-Glucosidase Inhibitory Activity

“…Compared to data reported in the literature, de Araújo et al [ 16 ] obtained MIC results greater than 1024 μg/mL, indicating that it is not clinically relevant. On the other hand, de Araújo et al [ 24 ] reported that the EO from C. heliotropiifolius Kunth presented inhibitory activity against Bacillus subtilis and Staphylococcus aureus , and de Araújo et al [ 25 ] reported inhibitory activity against Staphylococcus aureus by the EO from C. argyrophyllus .…”

Chitosan/Gelatin Scaffolds Loaded with Jatropha mollissima Extract as Potential Skin Tissue Engineering Materials

“…For phenols, values of 245 μg·mg −1 in J. mollissima leaf extract [ 26 ] and 58.07 mg·g −1 in its latex [ 27 ] are reported; these results differ from the results from the concentrations obtained here. Such differences can be explained by the difference in the parts of the plant used to prepare the extracts (leaves, flowers, bark, roots and latex) [ 48 , 49 ] and due to the vegetative cycle, botanical origin and climatic factors [ 50 ]. Therefore, the results confirmed the presence of the class of phenols, flavonoids and tannins metabolites in the EEJM, highlighting the tannins which presented a concentration of 431.68 mg·g -1 and may be one of the main groups of compounds responsible for the biological activities of J. mollissima latex.…”

Synergistic and Antibiofilm Effects of the Essential Oil from Croton conduplicatus (Euphorbiaceae) against Methicillin-Resistant Staphylococcus aureus

“…In our study, it was possible to identify and quantify 70 different chemical compounds, of which the monoterpenes 1,8 cineole (13.15%) and p-cymene (10.68%) were the majority, as well as the sesquiterpenes caryophyllene (9.73%) and spathulenol (6.36%). This variation in the chemical composition of the EOCC may be related to factors such as the specific location of leaf collection, growing season, botanical origin, climatic factors [ 25 ] and the drying process that was used on the plant material.…”