Chemodiversity and biological activity of essential oils from three species from the Euphorbia genus

Abstract

Several studies demonstrated the wide pharmacological properties of extracts and essential oils (EOs) prepared from Euphorbia species. In the present study, the chemical composition and biological activities of EOs from three different Euphorbia species were evaluated using in vitro methods. A total of 29, 33 and 42 constituents were identified in the EOs of E hirta, E convolvuloides and E heterophylla, respectively. The EOs exhibited in vitro radical scavenging potential in the ABTS assay (2.89‐21.50 mg/g). Additionally, an inhibitory effect on acetylcholinesterase (4.23‐5.12 mg/g) was detected. Besides, remarkable tyrosinase inhibition was reported by the EOs (95.24‐113.74 mg/g). Molecular docking was also performed to elucidate the binding interactions between selected EO components and enzymes. Phytol and geranyl‐(E)‐acetone had a good binding with tyrosinase in the molecular docking. This study highlighted the promising pharmacological profiles of these EOs as natural sources of antioxidants as well as cholinesterase and tyrosinase inhibitors that could be further explored in the management of human ailments in food and pharmaceutical industries.

Antiamylase, Antilipase, Antimicrobial, and Cytotoxic Activity of Nonea obtusifolia (Willd.) DC. from Palestine

“…Hereafter, herbal supplements and medications having high therapeutic efficacy with minimal side effects are much favored for patients. The antidiabetic agents from herbals are very promising, and traditionally acclaimed medicinal plants are being investigated for their antidiabetic potential [ 28 ]. Nearly 200 species of plant with hypoglycemic properties have been studied [ 29 ].…”

“…Example of these plants includes the ethanol fruits of cakile maritima scop. (brassicaceae) from Southern Portugal which showed to be 2.19 mmol of equivalent of acarbose [ 28 ].…”

Application of Essential Oils of Ocimum gratissimum and Cymbopogon citratus as Bioinsecticides for the Management of Two Major Biting‐Sucking Insects (Bemisia tabaci Gennadius and Jacobiella fascialis Jacobi) and the Improvement of Seed and Fiber Quality of Cotton Plants in Ivory Coast

“…In fact, the massive use of synthetic chemicals has a negative impact on the health of users and the environment. [9][10][11][12] To reduce their undesirable effects in the framework of green or organic agriculture, natural products such as aqueous, hydroalcoholic and oily extracts of certain plants, they have a lower health and ecological impact and thus preserve the most natural biodiversity. [13,14] To this end, essential oils, defined as the volatile components of aromatic plants, are a subject of several studies regarding in relation to their virucidal, [15] fungicidal, [16] insecticidal, [17] bactericidal [18] and herbicidal [19] effects.…”

“…According to Popp et al ., [6] Badiane et al [7] and Hussein et al , [8] the practice of chemical control of cotton pests is one of the factors of success that accompanied the development of the sector in West and Central Africa, it is however noted that the misuse of these synthetic agrochemicals threatens the sustainability of the production system. In fact, the massive use of synthetic chemicals has a negative impact on the health of users and the environment [9–12] . To reduce their undesirable effects in the framework of green or organic agriculture, natural products such as aqueous, hydroalcoholic and oily extracts of certain plants, they have a lower health and ecological impact and thus preserve the most natural biodiversity [13,14]…”

Pharmacological evaluation of Euphorbia hirta, Fagonia indica and Capparis decidua in hypertension through in-vivo and in vitro-assays

“…Numerous constituents like as caffeic acid, benzoic acid, epicatechin 3-gallate acid, quercetin, kaempferol, rutin, myricitrin, β-sitosterol, β-amyrin, euphorbin-A, euphorbin-B, euphorbianin, euphorbin-C, euphorbin-D, gamma-tocopherol, leucocyanidol, camphol, palmitic acid, shikmic acid, pentadecylic acid, gallic acid, niacin, protocatechuic acid, phytol, 24-methylene-cycloartenol, heptacosane, choline, tinyatoxin, squalene, afzelin and quercitrin [ 11 , 12 , 13 ], while dimethoxyageratochromone, n-haxadecanoic acid, caryophyllene oxide, hexahydrofarnesyl acetone and β-caryophyllene are major components of essentials oils (EOs) from E. hirta . The sesquiterpenes were found to be the predominant group of ingredients in the EOs of various Euphorbia species like E hirta, E convolvuloides and E heterophylla , these EOs as natural sources of antioxidants as well as cholinesterase and tyrosinase inhibitors [ 14 ].…”