Chemokine Fractalkine and Non-Obstructive Coronary Artery Disease—Is There a Link?
Aleksandra Stangret,
Karol Artur Sadowski,
Konrad Jabłoński
et al.
Abstract:Non-obstructive coronary artery disease (NO-CAD) constitutes a heterogeneous group of conditions collectively characterized by less than 50% narrowing in at least one major coronary artery with a fractional flow reserve (FFR) of ≤0.80 observed in coronary angiography. The pathogenesis and progression of NO-CAD are still not fully understood, however, inflammatory processes, particularly atherosclerosis and microvascular dysfunction are known to play a major role in it. Chemokine fractalkine (FKN/CX3CL1) is inh… Show more
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