Chemometric Analysis of Antioxidant and Mineral Elements in Colostrum of Native and Non-native Goat Breeds to Hypoxic Conditions at High Altitude

Kumar, Prabhat; Bharti, Vijay K.; Mukesh, Manishi

doi:10.1007/s12011-019-01940-y

Cited by 5 publications

(1 citation statement)

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“…The high level of TAC on the first day of life could be the consequence of colostrum intake. Colostrum of goats is a source of valuable nutritious compounds such as immunoglobulin, vitamins, minerals and antioxidants, which are essential for the survival of newborn kids in many diseases (Kumar et al, 2019). Furthermore, the low content of polyunsaturated fatty acids and high content of bilirubin and uric acid in the plasma may prevent the occurrence of oxidative stress in neonates (Gaal et al, 2006; Wiedemann et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

Age‐related changes in thyroid hormones, some serum oxidative biomarkers and trace elements and their relationships in healthy Saanen goat kids during the first three month of age

Valavi

Zaeemi

Mohri

2021

Animal Physiology Nutrition

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Background Early‐life diseases in dairy animals are main causes of economic loss in livestock production. Oxidative stress (OS) and thyroid hormones are important inter‐related components in the normal physiology of this critical period of life. However, limited information regarding their physiology in goat kids is available. This study was conducted to investigate the age‐related changes of thyroid hormones, some serum oxidative biomarkers and trace elements in healthy Saanen goat kids. Methods Nineteen newborn healthy Saanen goat kids (14 females and five males) were studied longitudinally from birth until three months of age. Blood sampling was performed 24–48 h after birth and was repeated on 10 ± 2, 28 ± 2, 56 ± 2 and 84 ± 2 days of age. The serum levels of thyroid hormones, malondialdehyde (MDA), reduced glutathione (GSH), total antioxidant capacity (TAC), selenium (Se), manganese (Mn) and molybdenum (Mo) were measured. Results Age‐related changes were observed for all measured variables except for MDA (p < 0.05). A decreasing trend was detected throughout the study in thyroid hormones, T3: T4 ratio and Mn (p < 0.01). Some factors decreased from birth to day 10 (Se) or day 28 (TAC and GSH) and followed by an increasing trend that extended to day 84 (p < 0.01). There were significant correlations between thyroid hormones and TAC, as well as Mn levels (p < 0.05). Conclusions These results imply that specific age‐related reference values are essential for proper interpretation of the serum level of thyroid hormones and Mn in Saanen goat kids during the first three months of life. In addition, given the high level of thyroid hormones particularly during the first days of life, and their relationship with oxidative biomarkers and trace elements, improving the antioxidant system in this critical period is essential.

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Section: Discussionmentioning

confidence: 99%