2024
DOI: 10.17776/csj.1351879
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Chemometric Determination of Parkinson's Drugs Containing Multiple Active Substances

Ayşe Merve Arslan,
Güzide Pekcan

Abstract: In this work, the active ingredients of Entacapone, Levodopa and Carbidopa in drug samples used in the treatment of Parkinson's disease were quantitatively determined by Ultraviolet Visible (UV-VIS) Spectroscopy and chemometrics. Firstly, the spectra of each drug active ingredient were taken individually and then synthetic mixtures identical to the drug sample were analyzed. In our method, validation parameters were calculated for each method. Percent (%) recoveries were found on average for both the synthetic… Show more

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