Chemoresponsive polymer systems for selective molecular recognition of organic molecules in biological systems

Catalyst-free synthesis of low-temperature thermally actuated shape memory polyurethanes with modified biobased plasticizers

“…Stimulus-responsive restoration of a polymeric material to its original shape after specific deformation has opened a new dimension in material applications. 1 These stimuli include, but are not limited to, changes in temperature, 2 light, 3 electricity, 4 pH, 5 and other similar variables. Biomedical devices such as cardiovascular stents, 6 sutures, 7 drug-eluting stents 8 and clot removal devices, 9 and tissue engineering, 10 have made extensive use of SMPs due to their biocompatibility, 11 biodegradability, 11 and human body temperature shape recovery.…”

Composite Dynamic Hydrogels Constructed on Boronic Ester Cross-Links with NIR-Enhanced Diffusivity

“…Dynamic hydrogels are referred to as smart, which results from their ability to respond to an external stimulus by the change of their macroscopic properties as a result of a change of their structure on the molecular level . Therefore, hydrogels constructed on reversible bonds are used as controlled drug delivery systems, − sensors, , and matrices for tissue engineering. , Most of the common hydrogels dedicated to biomedical applications are mainly chemoresponsive, i.e., they respond to the pH change, or the presence of organic compounds, redox agents, , etc. Temperature-sensitive hydrogels are the largest group among systems that respond to physical stimuli .…”

“…However, the materials that are responsive to light, electric, or magnetic fields also deserve our attention. The nature of certain cross-links can assure the dual- or multi-responsiveness of the material, which is exploited, for example, in the controlled drug delivery systems . Due to the robust development of numerous specific dynamic linkages, the construction of the material responsive to a concrete stimulus is not a problem.…”

Smart Hydrogels Meet Carbon Nanomaterials for New Frontiers in Medicine

“…Among their many properties, injectability, and self-healing are particularly sought after [ 17 ], as well as bioadhesion [ 18 , 19 ] and, obviously, biocompatibility [ 20 ]. Further, research is very active towards smart hydrogels that can adapt in response to changes in pH [ 21 ], temperature [ 22 ], light-irradiation [ 23 ], chemicals’ [ 24 ] or biomolecules’ [ 25 ] concentrations, as well as other physico-chemical stimuli [ 26 , 27 ]. A myriad of approaches has been developed to attain these properties, and, amongst them, a popular option consists of multi-component systems with nanofillers [ 28 ] to yield nanocomposite [ 29 , 30 ] or hybrid [ 31 , 32 ] hydrogels, so that new properties can emerge from the combination of the different constituents.…”