Chemoselective detection based on experimental and theoretical calculations of Cu2+ ions via deprotonation of chromone derived probe and its application

A novel “off–on” peptide fluorescent probe for the detection of copper and sulphur ions in living cells

“…Many fluorescent probes have been reported for the detection of Cu 2+ and S 2− , especially organic small molecule probes, such as: hydrazide, doped carbon dots, 2′,7′-dichlorofluorescein, imidazole dyes, Schiff base, naphthylamine, salamo, phenanthrene, and phenyl 2-(benzoylthio)benzoate. In contrast, 4,9,18–30 peptidic probes are better suited for bioassays and cellular imaging than most small-molecule probes because they are water soluble, biocompatible, low toxicity, and do not require organic solvents as co-solvents. See Tables S1 and S2 (ESI†) for more information.…”

A New Chromone‐based Sequential Functioning Colorimetric Chemosensor for Cu2+ and Cysteine in Near‐perfect Aqueous Media

“…Chromone derivatives, heterocyclic bioactive compounds, have distinct spectral properties and outstanding photostability [49–52] . Thiosemicarbazide derivatives prefer to form a complex with metal cations like copper and zinc because they contain nitrogen and sulfur donor atoms [53] .…”

“…[45][46][47][48] Chromone derivatives, heterocyclic bioactive compounds, have distinct spectral properties and outstanding photostability. [49][50][51][52] Thiosemicarbazide derivatives prefer to form a complex with metal cations like copper and zinc because they contain nitrogen and sulfur donor atoms. [53] Accordingly, we expected that the compound including both chromone and thiosemicarbazide moieties might operate as a colorimetry chemosensor for copper ions with distinct spectroscopic sensing properties.…”