Chemotherapy of Experimental Avian Mycoplasma Infections

Gale, G. O.; Layton, H W; Shor, A. L.; Kemp, G. A.

doi:10.1111/j.1749-6632.1967.tb27663.x

Cited by 7 publications

(3 citation statements)

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“…Protection assessed by mean weights confirmed the observations of Gale et al (1967) that tylosin protected against the growth depressing effects of Mg. It also supported the findings of Levisohn et al (1980) on tylosin and tiamulin that infected treated birds were heavier than untreated but lighter than uninfected stock.…”

Section: Discussionmentioning

confidence: 97%

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The minimum inhibitory concentration of kitasamycin, tylosin and tiamulin forMycoplasma gallisepticumand their protective effect on infected chicks

Jordan¹,

Knight²

1984

Avian Pathology

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The minimum inhibitory concentration (m.i.c.) of kitasamycin, tylosin and tiamulin for Mycoplasma gallisepticum (Mg) were compared with 10(6), 10(4), and 10(2) CFU/ml of the organisms with the drug incorporated in mycoplasma agar. The lowest m.i.c. was obtained with tiamulin and the highest with kitasamycin and, in general, the m.i.c.'s were directly influenced by the concentration of mycoplasmas. Chick embryos at 19 days of incubation were infected with Mg and the hatched infected chicks were used for comparing the protective effect of the three drugs. They were given in the drinking water when the chicks were 2, 3 and 4 days of age. Weight gains for the infected treated birds were similar for all three drugs; they were significantly lower than for those of uninfected chicks and significantly higher than for those of untreated infected chicks. However Mg could be isolated from a high proportion of chicks in the infected treated and untreated groups at 32 days of age.

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Section: Discussionmentioning

confidence: 97%

“…testing the protective effect of the antibiotics was perhaps more severe than necessary in view of the high morbidity and mortality among infected untreated chicks. However it probably simulates more realistically a natural congenital infection of Mg than airsac inoculation even at day-old (Gale et al, 1967).…”

Section: Discussionmentioning

confidence: 99%

The minimum inhibitory concentration of kitasamycin, tylosin and tiamulin forMycoplasma gallisepticumand their protective effect on infected chicks

Jordan¹,

Knight²

1984

Avian Pathology

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show abstract

“…Reports on the activity of drugs against PPLO are multiple (Domermuth, 1958(Domermuth, , 1960Domermuth and Johnson, 1955;Gale et al, 1967;Hamdy et al, 1957;Kumar et al, 1966;Olesiuk et al, 1956;Olsen et al, 1960;Perez, 1961;Van Roekel and Olesiuk, 1953), but published information on treatment of CRDC is scarce. Gross (1960) reported the activity of furaltadone in air sac disease with associated E. coli infection, and Lott (1960) strated the advantages of this drug in the same disease, when administered as an aerosol or in drinking water.…”

Section: Introductionmentioning

confidence: 95%