Chest Wall Tumors: Radiologic Findings and Pathologic Correlation

Tateishi, Ukihide; Gladish, Gregory W.; Kusumoto, Masahiko; Hasegawa, Tadashi; Yokoyama, Ryohei; Tsuchiya, Ryosuke; Moriyama, Noriyuki

doi:10.1148/rg.236015527

Cited by 192 publications

(104 citation statements)

References 54 publications

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“…Usually the mass forms obtuse angles with the pleural surface, but in the case of large masses the angle may be acute. Pleural effusions are not typically seen and destruction of underlying bone occurs rarely (18). …”

Section: Radiologymentioning

confidence: 99%

Solitary Fibrous Tumors of Chest: Another Look with the Oncologic Perspective

Saynak

Veeramachaneni

Hubbs³

et al. 2017

Balkan Med J

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Solitary ﬁbrous tumors are mesenchymal lesions that arise at a variety of sites, most commonly the pleura. Most patients are asymptomatic at diagnosis, with lesions being detected incidentally. Nevertheless, some patients present due to symptoms from local tumor compression (eg. of the airways and pulmonary parenchyma). Furthermore, radiological methods are not always conclusive in making a diagnosis, and thus, pathological analysis is often required. In the past three decades, immunohistochemical techniques have provided a gold standard in solitary ﬁbrous tumor diagnosis. The signature marker of solitary ﬁbrous tumor is the presence of the NAB2-STAT6 fusion that can be reliably detected with a STAT6 antibody. While solitary ﬁbrous tumors are most often benign, they can be malignant in 10-20% of the cases. Unfortunately, histological parameters are not always predictive of benign vs malignant solitary ﬁbrous tumors. As solitary ﬁbrous tumors are generally regarded as relatively chemoresistant tumors; treatment is often limited to localized treatment modalities. The optimal treatment of solitary ﬁbrous tumors appears to be complete surgical resection for both primary and local recurrent disease. However, in cases of suboptimal resection, large disease burden, or advanced recurrence, a multidisciplinary approach may be preferable. Specifically, radiotherapy for inoperable local disease can provide palliation/shrinkage. Given their sometimes -unpredictable and often- protracted clinical course, long-term follow-up post-resection is recommended.

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Section: Radiologymentioning

confidence: 99%

Solitary Fibrous Tumors of Chest: Another Look with the Oncologic Perspective

Saynak

Veeramachaneni

Hubbs³

et al. 2017

Balkan Med J

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“…Tumors of the chest wall are uncommon and include benign and malignant diagnoses [ 1 , 2 ] which can be further classified into those arising from bony structures and those of soft tissue origin. The clinical findings and the radiological appearance of soft tissue chest wall tumors has been previously reported in the literature [ 3 ] ; however, the appearance does not necessarily correlate with a specific diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Clinical utility of image-guided chest wall mass biopsy: results in 28 patients

Smith

et al. 2011

Cancer Imaging

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The purpose of our study was to determine the clinical usefulness of percutaneous image-guided biopsy of chest wall masses. A retrospective study of 28 patients who underwent image-guided biopsy of chest wall masses from 2005 to 2007 was performed. In 19 (68%) patients, the mass was detected as part of a staging evaluation in patients with known malignancy; 9 (32%) patients had no known malignancy. Biopsy results were classified as diagnostic (malignant or benign) or non-diagnostic (atypical and insufficient). Sensitivity, specificity and negative predictive value were calculated for all patients, and the Fisher–Freeman–Halton exact test was used to determine if test characteristics varied in patients with and without a history of cancer, masses smaller and greater than 5 cm, or according to needle size. The overall diagnostic rate was 71%. Of these, there were 20 true-positives, 3 true-negatives, 5 false-negatives and no false-positive results (sensitivity 80% (20/25), specificity 100% (3/3) and negative predictive value 37.5% (3/8)). There were no differences between patients with and without cancer. Among 19 patients with known cancer, 10 had metastatic disease from their known primary. Biopsy test characteristics did not differ with respect to mass or needle size. Minor complications were seen in 7% of patients. Image-guided chest wall mass biopsy is a sensitive and specific procedure, which is clinically important in the care of patients both with and without a known primary cancer.

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“…The male to female ratio is 3:2 [6]. It can involve almost any bone in the body; the most frequent sites of involvement are the femur, ilium, tibia, humerus, and fibula.…”

Section: Discussionmentioning

confidence: 99%

A Case of Ewing’s Sarcoma of the Clavicle in Adults

Zhou¹,

Tian²,

Yunus³

et al. 2013

IJCM

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The Clavicle is a rare primary site for Ewing sarcoma (ES). We report one case of patient with clavicular ES under our tracking and review the related literatures on management of this rare tumor. The patient was age of 35 years and was non metastatic at presentation. The patient received chemotherapy before and after the surgery. Claviculectomy was used. The patient had good functional outcomes with no pain of the shoulder at the follow-up of ten months. In conclusion, Ewing sarcoma of clavicle is a very rare tumor and different methods of surgical treatment can be used. Clavicle often can be resected without a need of reconstruction.

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Chest Wall Tumors: Radiologic Findings and Pathologic Correlation

Cited by 192 publications

References 54 publications

Solitary Fibrous Tumors of Chest: Another Look with the Oncologic Perspective

Solitary Fibrous Tumors of Chest: Another Look with the Oncologic Perspective

Clinical utility of image-guided chest wall mass biopsy: results in 28 patients

A Case of Ewing’s Sarcoma of the Clavicle in Adults

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