Chikungunya: A Paradigm of Emergence and Globalization of Vector-Borne Diseases

Simon, Fabrice; Savini, Hélène; Parola, Philippe

doi:10.1016/j.mcna.2008.07.008

Cited by 143 publications

(145 citation statements)

References 87 publications

Supporting

Mentioning

140

Contrasting

Unclassified

Order By: Relevance

“…9 Despite these uncommon findings, there has been a recent increase in reports describing neurologic manifestations of CHIK infections, mainly from Reunion Island and India, where a massive epidemic of CHIK involving millions of patients occurred. 5,6,8,11 Although this 2004-2009 CHIKV epidemic was caused by a variant virus of the central/eastern African genotype, 12,13 there has been no study to see whether this recent CHIKV strain is more virulent than the previous CHIKV of Asian lineages 14 Island-wide surveillance in Reunion Island identified 23 (1.4 per 1,000) adult patients with neurologic involvement among 16,050 laboratory-confirmed cases of CHIK infections. 15 The proportion of our neurologic cases (3 per 1,018) was slightly higher than that in Reunion Island but indicated that this complication was relatively infrequent, and the increased reports of neuro-chikungunya might be attributed to the exceptionally large number of patients involved during these outbreaks.…”

Section: Discussionmentioning

confidence: 99%

Case Reports of Neuro-Chikungunya in Southern Thailand

Chusri

Siripaitoon²,

Hirunpat³

et al. 2011

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

There has been a recent increase in reports of neurologic complications as major causes of morbidity and mortality in chikungunya virus infection. As a part of 2004–2009 global outbreaks, an unprecedented large chikungunya epidemic occurred in Southern Thailand during 2008–2009 in which 49,069 cases were reported. During this period, we encountered two patients with meningoencephalitis and another patient with myeloneuropathy among 1,018 cases diagnosed as chikungunya in our hospital. The clinical pictures are presented and the key points are used to recognize and differentiate chikungunya from Japanese encephalitis virus, dengue virus, and herpesvirus infections, which are more common causes of meningoencephalitis and myelitis in this region.

show abstract

Section: Discussionmentioning

confidence: 99%

Case Reports of Neuro-Chikungunya in Southern Thailand

Chusri

Siripaitoon²,

Hirunpat³

et al. 2011

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…Ae. albopictus has been implicated as a vector of the chikungunya virus, which is currently epidemic throughout much of the western hemisphere (Enserink 2006, Josseran et al 2006, Bonilauri et al 2008, Simon et al 2008. Ae.…”

mentioning

confidence: 99%

Interaction ofWolbachiaand Bloodmeal Type in Artificially InfectedAedes albopictus(Diptera: Culicidae)

Suh

Mercer

et al. 2016

J Med Entomol

View full text Add to dashboard Cite

Maternally inherited Wolbachia bacteria are being introduced into vector mosquito populations, with the goal of reducing the transmission of diseases such as dengue fever. The infection dynamics of Wolbachia depends upon the ability of Wolbachia to manipulate host reproduction as well as any fitness costs imposed upon the host. Some vector mosquito species are opportunistic blood feeders, utilizing both human and nonhuman vertebrate hosts, and the effects of bloodmeal source on Wolbachia phenotype is not well understood. Here we transfer wMelPop Wolbachia from Drosophila melanogaster (Meigen) into wild-type Aedes albopictus (Skuse) and characterize the resulting triple infection by examining for an effect of human and mouse blood on the Wolbachia infection persistence and phenotypes. When provided with human blood, the triple Wolbachia infection was persistent, with high maternal inheritance and relatively little fecundity cost, and a pattern of imperfect unidirectional cytoplasmic incompatibility was observed in mating experiments between wild-type and triply infected individuals. With mouse blood, reduced female fecundity and low maternal inheritance were observed in wMelPop-infected females, which affected the typical pattern of unidirectional CI. Our findings indicate the interactive effects of Wolbachia infection and blood source drive distinct shifts in the Wolbachia-host symbiotic association.

show abstract

“…The analogous (1E,4E)-1,5-bis(4-hydroxyphenyl)penta-1,4-dien-3-one and (1E,4E)-1-(2-hydroxyphenyl)-5-phenylpenta-1,4-dien-3-one, on the other hand, have been found to exhibit significant larvicidal activity against mosquito Aedes aegypti (L), [8] a known vector in the transmission of yellow fever, dengue haemorrhagic fever, and the re-emerging disease chikungunya. These compounds have also been found to inhibit binding of cholesterol to Aedes aegypti SCP-2 (AeSCP-2) in vitro [9]. Todate, the structures of the 1,1′-distyryl ketones have only been fully characterised using 1 H-NMR, 13 C-NMR, IR and UV spectrometric techniques and their trans stereochemistry was assigned based on the coupling constant values, J trans = 15.0-16.5 Hz [10].…”

Section: Discussionmentioning

confidence: 99%

Crystal structure of (1E,4E)-1,5-bis(4-chlorophenyl)penta-1,4-dien-3-one, C₁₇H₁₂Cl₂O

Maluleka

Mphahlele

2017

Zeitschrift Für Kristallographie - New Crystal Structures

View full text Add to dashboard Cite

CCDC no.: 1561907The crystal structure is shown in the figure. Tables 1 and 2 contain details on crystal structure and measurement conditions and a list of the atoms including atomic coordinates and displacement parameters. Source of materialA mixture of acetone (1.00 g, 17.2 mmol), 4-chlorobenzaldehyde (4.80 g, 34.5 mmol) and KOH (50%) in methanol 50 (mL) was stirred at room temperature for 2 h and then quenched with ice-cold water.

show abstract

Chikungunya: A Paradigm of Emergence and Globalization of Vector-Borne Diseases

Cited by 143 publications

References 87 publications

Case Reports of Neuro-Chikungunya in Southern Thailand

Case Reports of Neuro-Chikungunya in Southern Thailand

Interaction ofWolbachiaand Bloodmeal Type in Artificially InfectedAedes albopictus(Diptera: Culicidae)

Crystal structure of (1E,4E)-1,5-bis(4-chlorophenyl)penta-1,4-dien-3-one, C₁₇H₁₂Cl₂O

Contact Info

Product

Resources

About

Chikungunya: A Paradigm of Emergence and Globalization of Vector-Borne Diseases

Cited by 143 publications

References 87 publications

Case Reports of Neuro-Chikungunya in Southern Thailand

Case Reports of Neuro-Chikungunya in Southern Thailand

Interaction ofWolbachiaand Bloodmeal Type in Artificially InfectedAedes albopictus(Diptera: Culicidae)

Crystal structure of (1E,4E)-1,5-bis(4-chlorophenyl)penta-1,4-dien-3-one, C17H12Cl2O

Contact Info

Product

Resources

About

Crystal structure of (1E,4E)-1,5-bis(4-chlorophenyl)penta-1,4-dien-3-one, C₁₇H₁₂Cl₂O