Childhood Absence Epilepsy: Specific Features of the Disease Course and Outcomes

Schederkina, I. O.; Shadrova, A.A.; Заваденко, Н. Н.; Колтунов, И. Е.

doi:10.17749/2077-8333.2017.9.1.069-078

Èpilepsiâ paroksizmalʹnye sostoâ.

2017

DOI: 10.17749/2077-8333.2017.9.1.069-078

|View full text |Cite

Childhood Absence Epilepsy: Specific Features of the Disease Course and Outcomes

I. O. Schederkina

A.A. Shadrova

Н. Н. Заваденко

et al.

Abstract: Vol. 9 №1 www.epilepsia.su Данная интернет-версия статьи была скачана с сайта http://www.epilepsia.su. Не предназначено для использования в коммерческих целях. Информацию о репринтах можно получить в редакции. Тел.:

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Antiepileptic Drug Efficacy in Certain Genetic Types of Childhood Epilepsy

Marueva,

Shirshov,

Shil'nikova

et al. 2024

jour

View full text Add to dashboard Cite

Objective: we aimed to study antiepileptic drug efficacy in achieving seizure remission in certain genetic types of childhood epilepsy.Materials and methods. The authors studied 240 patients aged from 1 month to 18 years with epilepsy between 2019 and 2023. Children with genetic forms of epilepsy accounted for 69 (28,8%). In this group, remission was achieved in 13 (18,8%) of patients. Among them, there were 13 children (%) with certain forms of genetic epilepsy aged 5 to 4 (average 10 ± years), with 7 (53,8%) being girls and 6 (46,2%) being boys. There were 7 (53,8%) children with generalized epilepsy, including 5 (30,8%) cases of childhood absentee epilepsy. 5 (38,5%) patients had focal epilepsy, all of them had self-controlling epilepsy with central temporal adhesions. The study included one patient with an unspecified type of epilepsy (7.7%).Results. The duration of remission ranged from 6 months to 7 years 2 months (me – 3 years 8 months). 11 children (84,6%) were in stable remission for 1 year or longer. Complete clinical electroencephalographic remission was observed in 7 (53,9%) cases. In other cases, regional and diffuse epileptiform activity was recorded in 3 (75,0%) and 1 (25,0%) case, respectively. Remission was achieved in 5 children (38,5%) who were taking levetiracetam, 6 subjects (46,1%) – valproic acid, 1 person – carbamazepine (7,7%). Persistent remission was registered in 4 children (36,3%) who were prescribed levetiracetam, 5 children (45,4%) taking valproic acid and 1 person (9 %) who was administered carbamazepine. 1 person (7,7%) was in stable remission after discontinuation of the antiepileptic drug.Conclusion. Most of the children with certain types of genetic epilepsy under the treatment with antiepileptic drugs were in stable seizure remission. More than half of those observed were in a complete clinical electroencephalographic remission. Predominantly, seizure remission occurred with the administration of valproic acid and levetiracetam, with the same frequency in generalized and focal types of genetic epilepsy.

show abstract

Antiepileptic Drug Efficacy in Certain Genetic Types of Childhood Epilepsy

Marueva,

Shirshov,

Shil'nikova

et al. 2024

jour

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Childhood Absence Epilepsy: Specific Features of the Disease Course and Outcomes

Cited by 1 publication

References 0 publications

Antiepileptic Drug Efficacy in Certain Genetic Types of Childhood Epilepsy

Antiepileptic Drug Efficacy in Certain Genetic Types of Childhood Epilepsy

Contact Info

Product

Resources

About