Childhood atopy and mental health: a prospective, longitudinal investigation

Goodwin, Renée D.; Robinson, Monique; Sly, Peter D.; Holt, Patrick G.

doi:10.1017/s0033291716001896

Cited by 7 publications

(6 citation statements)

References 44 publications

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“…Children and adolescents with comorbid anxiety disorders and medical conditions are at a higher risk of developing mental health problems in adulthood, have poorer health outcomes and experience more limitations in social activities . A prospective, longitudinal investigation on childhood atopy and mental health on a population‐based birth cohort study in Australia found an association between allergies and increased vulnerability to affective and anxiety problems but no evident relationships between atopy and attention deficit hyperactivity disorder (ADHD) or externalizing problems . Knowledge of the comorbidity between anxiety and FA in children and adolescents is especially important since these disorders generally begin during infancy or childhood and may persist until adolescence or over, having profound effects on daily functioning and developmental pathways …”

Section: Results From the Selected Literaturementioning

confidence: 99%

“…53 allergies and increased vulnerability to affective and anxiety problems but no evident relationships between atopy and attention deficit hyperactivity disorder (ADHD) or externalizing problems. 54 Knowledge of the comorbidity between anxiety and FA in children and adolescents is especially important since these disorders generally begin during infancy or childhood and may persist until adolescence or over, having profound effects on daily functioning and developmental pathways. 53 Children with peanut allergy reported more fear of an adverse event and more anxiety about eating, especially when away from home, than peers with insulin-dependent diabetes mellitus.…”

Section: Anxiety In Children and Adolescents With Famentioning

confidence: 99%

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Anxiety and food allergy: A review of the last two decades

Polloni

Muraro

2020

Clin Experimental Allergy

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Food allergy (FA) is recognized as a growing public health burden affecting 5%‐10% of children worldwide. Several unique features specific to FA elicit high levels of emotional distress and anxiety in patients and caregivers, the first among all the possibility of a life‐threatening reaction. Anxiety disorders are highly prevalent in patients with chronic disease, but remain undertreated despite significant negative consequences on patient health. This review aimed to offer a comprehensive overview of literature data on FA and anxiety of the last two decades. A review of the medical and psychological literature from the year 2000 (MEDLINE, PubMed and PsycINFO) was done using the keywords “anxiety” and “food allergy.” Clinical implications for disease management, various manifestations in different target groups, proper interventions and possible explanations on the nature of the association between FA and anxiety have been discussed, as well as limitations and further research directions. The relationship between FA and anxiety is attributed to FA‐specific fears and anxiety, rather than a general propensity towards anxiety. Some anxiety—short‐lived and related to key events–is to be expected and may even be helpful if it sustains allergen avoidance and preparedness to emergency. However, some data reported that increased anxiety did not improve adherence. Rather, high levels of anxiety have been demonstrated counterproductive and related to maladaptive coping. Further research is needed to elucidate the association between FA and anxiety, especially to understand biopsychosocial directions of the underlying mechanisms and to build proper, effective, standardized protocols of intervention. Clinicians must be aware of the association between FA and anxiety, understand their role in recognizing maladaptive anxiety and encouraging to seek psychological support when needed.

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Section: Results From the Selected Literaturementioning

confidence: 99%

Section: Anxiety In Children and Adolescents With Famentioning

confidence: 99%

Anxiety and food allergy: A review of the last two decades

Polloni

Muraro

2020

Clin Experimental Allergy

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“…14 In part, this might explain the high levels of overlap between NCDs, such as allergic diseases and mental disorders. 14,15 The emerging science of the microbiome and its influence on early-life immune priming to be discussed below has forced a total environment perspective.…”

Section: Beyond the Genomementioning

confidence: 99%

An exposome perspective: Early-life events and immune development in a changing world

Renz

Holt

Inouye

et al. 2017

Journal of Allergy and Clinical Immunology

174

150

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Advances in metagenomics, proteomics, metabolomics, and systems biology are providing a new emphasis in research; interdisciplinary work suggests that personalized medicine is on the horizon. These advances are illuminating sophisticated interactions between human-associated microbes and the immune system. The result is a transformed view of future prevention and treatment of chronic noncommunicable diseases, including allergy. Paradigm-shifting gains in scientific knowledge are occurring at a time of rapid global environmental change, urbanization, and biodiversity losses. Multifactorial and multigenerational implications of total environmental exposures, the exposome, require coordinated interdisciplinary efforts. It is clear that the genome alone cannot provide answers to urgent questions. Here we review the historical origins of exposome research and define a new concept, the metaexposome, which considers the bidirectional effect of the environment on human subjects and the human influence on all living systems and their genomes. The latter is essential for human health. We place the metaexposome in the context of early-life immune functioning and describe how various aspects of a changing environment, especially through microbiota exposures, can influence health and disease over the life course.

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“…Atopic diseases, including allergic rhinitis 2 , asthma 3 , atopic eczema/dermatitis 4 , and urticaria 5 are common in children and present many management challenges for their caregivers 6 – 8 . Allergies are immune responses and usually involve chronic inflammation 9 . However, whether inflammation and irritation increase the risk of neuropsychological consequences in children with atopic diseases is still unclear 10 – 12 .…”

Section: Introductionmentioning

confidence: 99%

Allergic diseases do not impair the cognitive development of children but do damage the mental health of their caregivers

Kuo

Chang

Tsai

et al. 2020

Sci Rep

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This study aimed to investigate whether children with atopic diseases exhibited different neurodevelopment function from healthy controls and whether their caregivers had differential parental stress. In total, we recruited 109 patients with atopic diseases (mean age 6.8 years, 54.1% male) and 82 healthy children (mean age 6.3 years, 54.9% male). Based on the children’s age, they underwent developmental, cognitive evaluations and attention deficit/hyperactivity disorder (ADHD) symptoms. The parenting stress of children’s caregivers was evaluated using the Chinese Health Questionnaire (CHQ-12) and Family APGAR. Of the children with atopic diseases, 87.2%, 74.3%, 29.4%, and 8.3% of them had allergic rhinitis, asthma, atopic dermatitis, and urticaria, respectively. None of these conditions were associated with children’s cognitive profiles or ADHD symptoms. However, the caregivers of patients who had asthma suffered from higher CHQ-12 scores than those of patients without asthma. Furthermore, the number of atopic diseases had a dose–response effect on caregivers’ CHQ-12 scores. In conclusion, allergic diseases did not impair the cognitive development of children. However, caregivers of patients with asthma or multiple atopic diseases may suffer a greater mental health burden with regard to caring for their children. Such caregivers may require support to effectively fulfill their parenting roles.

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Childhood atopy and mental health: a prospective, longitudinal investigation

Cited by 7 publications

References 44 publications

Anxiety and food allergy: A review of the last two decades

Anxiety and food allergy: A review of the last two decades

An exposome perspective: Early-life events and immune development in a changing world

Allergic diseases do not impair the cognitive development of children but do damage the mental health of their caregivers

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