Childhood brucellosis in north-western Greece: A retrospective analysis

Galanakis, E; Bourantas, Konstantinos L.; Leveidiotou, S.; Lapatsanis, P

doi:10.1007/bf02115616

Cited by 38 publications

(32 citation statements)

References 14 publications

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“…Bruselloz, hafif formdan fatal formlara kadar değişebilen spektrum-da klinik tablolara neden olabilen sistemik bir enfeksiyon hastalığı olup klinik belirti ve bulgular çoğunlukla özgün değildir (5,6). En sık yakınmalar ateş yüksekliği, artralji ve terlemedir (6,12). Çalışmamızda literatürle uyumlu olarak ateş yüksekliği, artralji, halsizlik ve terleme en sık başvuru yakınmaları idi.…”

Section: Discussionunclassified

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Brucellosis in Childhood

Çelebi¹,

Hacımustafaoğlu²,

Demirtas³

et al. 2011

J Pediatr Inf

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Objective: Brucellosis is still an important infectious disease, being widespread as endemic and sporadic cases in Turkey. The aim of this study was to evaluate clinical and laboratory findings, treatment modalities and final outcomes of brucellosis in children. Material and Methods: This is a retrospective record review of all patients 0-18 years of age with brucellosis admitted during a 8-year period between January 2003 and September 2010. Results: Of the 62 patients, 39 (63%) were male. The mean age and standard deviation of patients was 120±51.7 months (4 months-18 years). Most common symptoms on admission were fever (88%), arthralgia (64%) and dizziness (19%). On physical examination, the findings and percentages were as follows; arthritis (29%), lymphadenopathy (25%), hepatomegaly (24%) and splenomegaly (17%). Fiftyone percent of the patients had high sedimentation rate, 41% had high transaminase levels, and 40% had positivity for C-Reactive Protein. Brucella agglutination tests were positive in all cases. Brucella spp. was isolated from blood cultures in 27% of the cases. All of the cases were given combined drug therapy. Three of the cases (4.8%) had relapses during the follow up period. No mortality was seen in patients with brucellosis. Conclusion: Childhood brucellosis remains an important public health problem in our country. It may cause serious complications in children, and treatment with at least two antibiotics for not less than six weeks appears to be effective. (J Pediatr Inf 2011; 5: 59-62)

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Section: Discussionunclassified

“…Bruselloz olgularında akut faz reaktanları genellikle orta derecede artmaktadır (5,12). Çalışmamızda ESR yüksekliği %52, CRP pozitifliği %40.3 ve transaminaz yüksekliği %42 olguda saptandı.…”

Section: Discussionunclassified

Brucellosis in Childhood

Çelebi¹,

Hacımustafaoğlu²,

Demirtas³

et al. 2011

J Pediatr Inf

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“…A PUBMED search of the English language literature revealed 5 previous reports of brain abscess caused by Brucella spp. in children (7)(8)(9)(10)(11). Six brain abscesses were documented (7) in a 4-year-old boy who had headache and papilledema that persisted after a full course of therapy with oral tetracycline plus streptomycin was given to treat the brucellosis.…”

Section: Discussionmentioning

confidence: 98%

Brucellar Brain Abscess in a Child

Çelebi¹,

Hacımustafaoğlu²,

Sınırtaş³

2010

J Pediatr Inf

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ÖzetBrusellozla uyumlu bulguları gelişen 10 yaşındaki erkek olguya tetrasiklin ve streptomisin kombine tedavisi verildi. Tedaviye rağmen olguda ani başlangıçlı konuşma bozukluğu ve ölüm korkusu gelişmesi üzerine çekilen kraniyal magnetik rezonans görüntülemesinde abse saptandı. Olgunun kan kültüründe Brucella abortus üremesi oldu. Doksisiklin ve rifampisin tedavisi ile olgu tamamen düzeldi. (Çocuk Enf Derg 2010; 4: 89-91) Abstract A ten-year-old boy developed symptoms consistent with brucellosis and was treated with combined tetracycline and streptomycin. Despite therapy, he abruptly developed dysarthria and fear of death. A cranial magnetic resonance imaging revealed an abscess. Brucella abortus was isolated from the blood culture. He recovered completely with doxycycline plus rifampicin therapy. (Çocuk Enf Derg 2010; 4: 89-91)

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“…It is a systemic disease that can affect any part of the body,45 with nonspecific complaints, with a paucity of physical findings, and with an onset that can be insidious or acute. Symptoms begin 2 to 4 weeks after exposure—mainly fever, sweating, malaise, lethargy, anorexia and joint pains 6–14…”

Section: Discussionmentioning

confidence: 99%

Soft tissue mass of the chest wall as the sole manifestation of brucellosis in a 7-year-old boy

Al-Ayed

Bin-Hussain

Hajjar

et al. 2011

Annals of Saudi Medicine

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We report the case of a child who presented with a subcutaneous mass on the left side of the chest wall of one month's duration. The mass was painful and increasing in size over time. He had a history of weight loss and a decrease in appetite, but no history of fever or trauma. He had ingested raw camel milk, but had no history of contact with animals. He was diagnosed by the standard tube agglutination titer and tissue culture for brucellosis, treated with surgery and three months of antibrucella antibiotics. The report includes a brief review of the current pediatric literature to familiarize pediatricians with this uncommon presentation.

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Childhood brucellosis in north-western Greece: A retrospective analysis

Cited by 38 publications

References 14 publications

Brucellosis in Childhood

Brucellosis in Childhood

Brucellar Brain Abscess in a Child

Soft tissue mass of the chest wall as the sole manifestation of brucellosis in a 7-year-old boy

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