Childhood constipation: longitudinal follow-up beyond puberty

Ginkel, Rijk van; Reitsma, Johannes B.; Büller, Hans A.; Wijk, Michiel P. van; Taminiau, J. A. J. M.; Benninga, Marc A.

doi:10.1016/s0016-5085(03)00888-6

Cited by 321 publications

(282 citation statements)

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“…2,3 Constipation can become chronic in up to one-third of patients and persist into the adult life. 4 If children under 5 years of age suffer from constipation, it is especially likely to become chronic over time, resulting in frequent visits to medical centers later in life. 3,5 Thus, if young children suffer from repeated constipation events, it is important to evaluate the symptoms and to provide appropriate treatment.…”

Section: Introductionmentioning

confidence: 99%

Value of 24-hour Delayed Film of Barium Enema for Evaluation of Colon Transit Function in Young Children with Constipation

Yoo

Son

Park

et al. 2016

J Neurogastroenterol Motil

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Background/AimsA colon transit time test using radio-opaque markers (CTTRM) is considered the gold standard for evaluating colon transit function. A 24-hour delayed film of barium enema (BE) has been used as a supplementary method in structural evaluations. The aim of this study was to evaluate the utility of a 24-hour delayed BE film for assessing colon transit function in young children with constipation. MethodsIn total, 93 children with constipation who performed both single-contrast BE and CTTRM were enrolled in this study. Of these, the data from 70 children were analyzed (males 33, females 37; mean age [range], 5.63 ± 2.94 [2-14] years). The basic principle of the study is "velocity = distance/time". Time values were identified in both studies, and the colon length and distance of barium movement were measured on the 24-hour delayed BE film. Thus, colon transit velocity values could be calculated using both methods. The correlation between colon transit velocity using a 24-hour delayed BE film versus CTTRM was analyzed statistically. ResultsMedian value (interquartile range) of colon transit velocity using CTTRM was 1.57 (1.07-2.89) cm/hr, and that using BE of that was 1.58 (0.94-2.07) cm/hr. The Spearman correlation coefficient was 0.438 (P < 0.001) for the overall group. The correlation was strongest in children younger than 4 years (r = 0.537, P = 0.032). ConclusionsAlthough the correlation between BE and CTTRM was not very strong, the 24-hour delayed BE film could provide broad information about colon transit function in young children, especially those under 4 years who usually cannot undergo CTTRM.

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Section: Introductionmentioning

confidence: 99%

Value of 24-hour Delayed Film of Barium Enema for Evaluation of Colon Transit Function in Young Children with Constipation

Yoo

Son

Park

et al. 2016

J Neurogastroenterol Motil

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“…Constipation is also considered to associate with child and family anxiety, emotional disorders and depression (11).…”

Section: Introductionmentioning

confidence: 99%

Comorbidity of headache and functional constipation in children: A cross-sectional survey

Inaloo

Dehghani²,

Hashemi³

et al. 2014

Turk J Gastroenterol

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Background/Aims: Constipation and headache are prevalent conditions among children worldwide. Previous studies have shown the relationship between upper gastrointestinal complaints and headache in children. However, the association with lower gastrointestinal complaints such as constipation has not been investigated until present. The aim of this study is to evaluate the relationship between headache and chronic functional constipation in children aged 4-12 years old. Materials and Methods: This cross-sectional study has evaluated the prevalence of headache in 326 children in Shiraz, Iran 2012. All the subjects and their parents were interviewed based on a structured questionnaire for the diagnosis of constipation and headache. Children with constipation were selected from the Pediatric Gastroenterology Clinic Affiliated to the Shiraz University of Medical Sciences. The control group was selected from healthy children attending Shiraz schools. Diagnosis of headache and constipation were made based on the second Edition of The International Headache Classification (ICHD-2) and ROME III criteria, respectively. Results: Headache prevalence among children with constipation was significantly higher (19.8%) than that of the control group (5.6%) [Odds ratio (OR) 4.192, p<0.001], which was significant only in the non-migraine headache subtypes (15.1% vs 2.8%, OR 25, p<0.002). Among the headache subtypes of different severity (mild, moderate, severe), only mild headache was significantly more prevalent in constipated children (14.9% vs. 1.4%, in the control group, respectively, p<0.001). Conclusion: This study revealed a strong correlation between headache and chronic functional constipation, which can result from the effect of these comorbid conditions with emotional stress, depression, and anxiety.

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“…Противоречивые дан-ные получены о соотношении полов у детей, страдающих запором. Некоторые исследования сообщили о большем числе страдающих запорами мальчиков по сравнению с девочками [15], но в возрасте до 4 лет соотноше-ние мальчиков и девочек составляет, как правило, 1:1. По данным исследования, проведенного в Азии, зна-чительно выше распространенность запора у девочек в возрасте 3-5 и 7-12 лет по сравнению с мальчиками [16].…”

Section: эпидемиологияunclassified