Childhood Hodgkin's disease in Campinas, Brazil

Comparison of treatment outcomes of childhood Hodgkin lymphoma in two US centers and a center in Recife, Brazil

“…This is consistent with findings in other LIC 16–18. Some studies have shown that mixed cellularity histology is associated with a worse prognosis, others have not 16,19. Histology, sex, and age were not associated with outcome in this study.…”

A chemotherapy only therapeutic approach to pediatric Hodgkin lymphoma: AHOPCA LH 1999

“…HL in LIC is more frequent than in HIC, presents at an earlier age, and has a larger proportion of mixed cellularity histological type and a higher proportion of males . The current report from AHOPCA confirmed these characteristics.…”

“…In a report of children treated for HL in Campinas, Brazil, the patients referred to the center for treatment had a predominance of mixed cellularity histology. However, when the patients were reviewed at the center by two experienced hematologists, the majority of patients had nodular sclerosis HL [6]. Similarly, as we have gained experience in AHOPCA, we have been diagnosing a lower proportion of mixed cellularity HL [16].…”

Hodgkin disease in children: Results of a prospective randomized trial in a single institution in Argentina

“…Recently, Faría et al published a small series of patients from Brazil treated for Hodgkin disease with an OS estimate of 0.78 [35]. They mentioned that these results were lower than developed countries data [2,4,19], but similar to other underdeveloped countries [32,[36][37][38].…”