Childhood leukemia around French nuclear power plants—The geocap study, 2002–2007

Sermage-Faure, Claire; Laurier, Dominique; Goujon-Bellec, Stéphanie; Chartier, Michel; Guyot-Goubin, Aurélie; Rudant, Jérémie; Hémon, Denis; Clavel, Jacqueline

doi:10.1002/ijc.27425

Cited by 90 publications

(80 citation statements)

References 39 publications

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“…After Sellafield, increased childhood leukemia risk was found at nearly all the nuclear sites where studies were carried out [7][8][9][10] and a very large study from Germany also confirmed a statistically significant excess risk [8]. The latest COMARE 17 th report continues to dismiss the possibility that the radiation exposures can be the cause of the leukemias, and for the same reason, the doses are too low [10].…”

Section: Discussionmentioning

confidence: 99%

“…Since childhood leukemia has been associated in many studies [4][5][6][7][8][9][10] with proximity to nuclear sites, in particular fuel reprocessing sites like Sellafield in the UK [10] it seems possible that radioactive exposures of some kind may be reasonably investigated as a cause. The largest injection of radioactivity into the global environment was the atmospheric nuclear testing that was carried out in the period 1950-1963 when the fallout contamination peaked in 1959-63.…”

Section: Introductionmentioning

confidence: 99%

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Childhood leukemia, atmospheric test fallout and high voltage power distribution lines

Busby¹

2017

Pediatr Dimensions

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An association between increased rates of childhood leukemia and proximity to high voltage electricity power transmission lines was found in a 2005 study by Draper et al. More recently, this study was extended to include a further period of time and with an enlarged dataset by Bunch et al 2014, the result being that there was no longer any overall statistically significant effect for the whole period. Using the data from these two studies the trend in Relative Risk with fallout dose is examined for five sub-periods 1962-69, 1970-79, 1980-89, 1990-99 and 2000-2008. The effect turns out to be significantly associated with the levels of radioactive fallout from atmospheric testing (Chi-square for trend = 7.6; p = 0.006). A non-linear association between the Relative Risk and the Fallout doses is robust, R 2 = 0.955; F-statistic 65.6; p = 0.004. Fews et al. (1999) raised the issue of the concentration of airborne radioactive particles near power lines and it is suggested that the observed trend in Relative Risk with time supports a hypothesis in which the inhalation of radioactive particulates from fallout may be the cause, or related to the cause of the effect. The hypothesis is extended to a general discussion of child leukemia and radiation which implicates particulates.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Childhood leukemia, atmospheric test fallout and high voltage power distribution lines

Busby¹

2017

Pediatr Dimensions

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“…4 and the discussion of the Geocap study. 2 Adjusting for community type did not alter the odds ratio for ''distance'' in Germany ( Table 1).…”

Section: Dear Sirmentioning

confidence: 93%

“…2 The Geocap study used a similar design as the KiKK study: in a case-control study, the distance to the next nuclear power plant was used as a surrogate for potential exposure to ionizing radiation from the plant. The Geocap study had two major extensions compared to the German study: cases and controls up to age 15 were included in the study (in Germany, the age limit was 5 years) and a further classification of exposure according to a so-called ''Dose-Based Geographical Zoning'' was performed.…”

Section: Dear Sirmentioning

confidence: 99%

The German and the French studies on childhood leukemia and nuclear power: Differences and similarities

Spix¹,

Kaatsch²,

Blettner³

2012

Intl Journal of Cancer

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Silver nanoparticles were produced by a chemical reduction method that reduced silver nitrate with reducing agents such as hydrazine and glucose. The silver nanoparticles were characterized with transmission electron microscope, scanning electron microscope, and optical microscope. The effects of process parameters such as the stirring speed, temperature, type of reducing agent, and dispersing agent on the particle size were studied. The particle size decreased with an increase in the stirring speed and a decrease in the process temperature. Smaller particles were formed when the silver nitrate was reduced by glucose versus those that were formed by reduction with hydrazine. Silver nanoparticles with average sizes of 10 and 35 nm, produced by reduction with hydrazine at 5 and 40°C, were applied to silk by an exhaust method. Silk fabrics treated with 40 ppm silver hydrosol produced at 5°C and 60 ppm silver hydrosol produced at 40°C showed 100% antimicrobial activity against the gram‐positive bacterium Staphylococcus aureus. The durability of the antimicrobial property of the treated silk fabric to washing was also examined and is presented. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008

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“…1 They particularly commented on the standardized incidence ratio (SIR) we showed in Table 2 for children less than 5-years-old over the whole study period [1990][1991][1992][1993][1994][1995][1996][1997][1998][1999][2000][2001][2002][2003][2004][2005][2006][2007] Table 2). …”

Section: Dear Editormentioning

confidence: 99%